Medicinal mushrooms have had a long and celebrated tradition throughout Asia, in fact over 200 species are commonly used in Chinese medicine. Examples of medicinal mushrooms are Reishi, Chaga, Cordyceps, Maitake, Coriolus, and the mushroom compound AHCC, to name a few popular ones. Medicinal mushrooms have been well-researched for their immune enhancing and anti-cancer properties. Most recently, research has emerged showing that medicinal mushrooms can help eradicate HPV, dramatically impacting the clearance rate of the virus.
Research from France showed that HPV-positive patients (HPV 16 and 18) who were treated with two variety of medicinal mushrooms Turkey Tail and Reishi, tested negative for HPV after two months of treatment. In another study from the University of Texas Medical School, ten HPV positive women were treated with AHCC, a mushroom extract for six months and at the end of the study, 8 out of the 10 patients were confirmed to have eradicated HPV. It is for this reason, that Papillex has included medicinal mushroom extract in its formulation.
Mushrooms’ therapeutic potency can be owed to its several active ingredients; polysaccharides, triterpenes, polyphenols and phytosterols. In order for our bodies to absorb and benefit from these super foods, the active ingredients must be extracted, if not, they are deemed indigestible with little to no benefits. The active ingredients found in mushrooms are locked away in a covering called Chitin, the same material that forms insects, lobsters and crab shells. This compound is indigestible by humans, making it almost impossible to access the active ingredients in non-extracted mushrooms.
To be most effective, medicinal mushrooms must be standardized to the immune activating component, polysaccharides. The higher the % polysaccharides, the better.
The most common extraction technique is hot water extraction. The hot water is able to melt the Chitin and release the water-soluble active compounds. It can be quite expensive to extract biologically active compounds and for this reason, quite a few supplement companies contain limited or no bioactive compounds at all. Papillex uses a dual extract method of medicinal mushrooms, delivering the immune enhancing, high polysaccharide active form to our customers.
Smith JA, et. al. Evaluation of active hexose correlated compound (AHCC) for the Eradication of HPV Infections in Women with HPV positive Pap Smears. Phase 2 Clinical Trial: Source
Donatini B. Control of Oral Human Papillomavirus (HPV) by Medicinal Mushrooms, Trametes versicolor and Ganoderma lucidum: A PreliminaryClinical Trial. Int J Med Mushrooms. 2014;16(5):497-8. Article