HPV – Human Papilloma Virus Infection 101

By Papillex January 19, 2010

HPV stands for human papillomavirus. It is a non-enveloped DNA virus and belongs to the papovaviridae virus family. HPV causes warts and carcinoma of the cervix and penis.

Hundreds of types of HPV have been identified through DNA fragment analysis. These have been subdivided into low-risk types and high-risk types. The low-risk types are responsible for the growth of warts in human beings while the high-risk types may progress into cancer.

The genes, E6 and E7 are implicated in carcinogenesis. These inactivate the proteins encoded by the tumor suppressor genes, p53 and Rb (retinoblastoma) gene respectively.

The mode of transmission is through skin-to-skin contact and sexual contact. HPV is highly contagious, that is, the infection passes from an infected person to an uninfected person easily.

HPV infects the squamous epithelial cells and causes koilocytosis. It causes benign tumors of squamous cells, which usually do not progress to malignancy. Persistent HPV infections caused by high-risk HPV types can progress into cancer.

HPV can be diagnosed by:

  • Extraction of DNA from the cervical cells collected by brushing the cervix.
  • Detection of viral DNA sequences by DNA hybridization.

The tests available for the diagnosis are:

  • Pap test.
  • HPV test.

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The ingredients present in Papillex provide nutrient support and immune-system modulation. It nutritionally supports the elimination of genital warts, cervical dysplasia and other HPV related diseases.

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